Get to the Top of the Clock Tower
You must now make your way to the top of the Clock Tower, first climbing the stairs and then later hopping aboard an Elevator. For starters, though, there's the statue of Salazar to deal with. It'll breathe fire at you, making getting around it a lot tougher. However, if you can get behind it, there's a little opening in the back of its head you can shoot that makes it explode. When you're climbing the scaffolding around it, you can manipulate the head into turning away from you, making the explosives in its head an easy target. Once you destroy it, the next threat will be giant boulders tumbling down the staircase.
Use the little balconies on the side of the staircase to avoid taking any damage from them, then kill the Zealot controlling them once you've made your way up. When you can't go any further, climb down to your left to the Elevator. Before operating it, though, grab the Mirror with Pearls & Rubies and Extravagant Clock. Now pull the lever and you'll start heading up. Enemies will now routinely flood into the Clock Tower on the floors above you, either shooting at you from a distance or dropping down onto the Elevator itself. Simply kill them all as you go, taking advantage of the red barrels when you can.
When you reach the top, follow the path outside and you'll spot Salazar and Ashley below.
Go After Ashley
Continue following the path around the side of the Clock Tower, making sure to carefully walk instead of running over the parts that shake under your feet. If you do run, it's an automatic death. Grab the Yellow Diamond halfway along and then kill the Zealots up ahead. You can also pay the Merchant a visit on your left before progressing.
When you're prepared, go down the stairs outside and through the door you saw Salazar use. It's now time for a boss fight with him. The vertically challenged villain has turned into a monster, and now it's time to put an end to its reign.
The boss will be able to freely move about the arena, using its tentacles and many arms to position itself both near to you and high up in the air. For much of the encounter, it'll be protected by flesh covering a weak spot, which is essentially Ramón himself. Watch out for the black liquid it places on the floor, as it'll blow up in your face and deal damage.
The best strategy is to continually damage the boss until its weak spot opens up. If it's close by, the Striker is a great pick while the Stingray with a Scope attached allows you to hurt it from far away. Alternatively, if you can afford it, the Rocket Launcher is a one-hit kill. Upon dealing enough damage, the boss will be staggered and drop to the floor; this allows you to get in close and stab its weak spot. After doing this four or so times, Ramón Salazar will be no more.
Go After Ashley
After killing the boss, sweep the arena for any supplies left over and then leave the Ancient Chantry via the drawbridge. Destroy the breakable barrels before heading down in the Elevator. At the bottom, you can collect the supplies as you make your way through to the dock. Interacting with the Boat there finishes Chapter 12.
Did you find our Chapter 12 walkthrough for Resident Evil 4 useful? Click through to our Resident Evil 4 Remake guide for more information and share any further tips in the comments below.