Naturally, this is pretty bad as Mass Effect 2 is a sprawling 30-hour RPG epic. Bioware says it's aware of the problem and hopes to have a patch submitted to Sony as soon as possible. Until then, the developer reckons restarting the game every few hours should help you to avoid the nasty bug.
Reaper what you sow
Spans three eras of lore starting 17th November
Expect customisation and cop chases
We just don't know which right now