Want to know how to open the Safe in Downtown in The Last of Us 1? In order to open the Safe, you'll first need to learn the Safe code combination. As part of our The Last of Us 1 guide, we're going to provide a walkthrough for this puzzle, so that you can learn how to open the Safe in Downtown.

The Last of Us 1: How to Open the Safe in Downtown

The Last of Us 1: How to Open the Safe in Downtown Guide 3
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In the Downtown chapter, you'll end up in a subway, around the time you collect a Molotov for the first time. You'll reach a waiting room area with a selection of stores, which is inhabited by Clickers and Runners. We'd recommend you deal with these first, before proceeding with how to open the Safe in Downtown.

Once the area is clear, go inside the medicine shop on the left of the waiting room, and collect the Artefact named Note to Derek. This has the Safe code combination written on it, which is 03-43-78. Now, on the opposite side of the room, you'll find a shop called Round Note. Underneath the counter, is the Downtown Safe location, where you can input the code.


Do you now know how to open the Safe in Downtown in The Last of Us 1? For all Safe code combinations, refer to our The Last of Us 1 guide for more information.