What are all Symbiote Nests locations in Marvel's Spider-Man 2? A type of Mission, you'll need to find and complete all of them to achieve 100% completion across all Districts. As part of our Marvel's Spider-Man 2 guide, we are going to reveal all Symbiote Nests locations. Finishing them all unlocks the Exterminator Trophy.

Marvel's Spider-Man 2: All Symbiote Nests Locations

Marvel's Spider-Man 2: All Symbiote Nests Locations Guide 1

There are 10 Symbiote Nests in the game. You'll unlock them towards the end of the Main Story, when Venom begins taking over the city with his tendril network. At each Symbiote Nest, you must plant Sonic Bursts on the fleshy parts on the ground and then defend them until the countdown timer reaches zero. Symbiotes will attack you, and you must stop the Sonic Burst Integrity from reaching zero while the timer counts down. The Symbiote Nests are very easy to spot in the open world as their huge red tendrils stick out into the sky. Below you'll find all Symbiote Nests locations.


Towards the east of Astoria.

Upper East Side #1

On the eastern border of Upper East Side, right next to the water.

Upper East Side #2

In the northwest corner of Upper East Side.

Harlem #1

In the southeast corner of Harlem.

Harlem #2

In the middle of Harlem.


In the southwest of Chinatown near the bridge to Williamsburg.


Towards the south of Williamsburg.

Little Odessa

In the southern area of Little Odessa.

Financial District

In the northwest corner of the Financial District.

Upper West Side

On the western side of the Upper West Side, slightly heading south.

Did you find our guide to all Symbiote Nests locations useful? For more information on Marvel's Spider-Man 2, including all Collectibles, check out our Marvel's Spider-Man 2 guide through the link.