Dragon Quest XII: The Flames of Fate has been announced, and it certainly sounds interesting. It's been described as "Dragon Quest for adults" by series creator Yuji Horii. It'll apparently have player choices that can change the story, and a "new" combat system. Those familiar with Dragon Quest will know that the mainline games have always had turn based battles — but it sounds like this is changing, at least to some degree.
Square Enix is aiming for a simultaneous worldwide release for Dragon Quest XII — but no platforms or dates were announced. Based on Horii's comments, it seems like the game's still quite early in development.
Hopefully we hear more soon!