Uncharted 2: Among Thieves: Officially Pushing Playstation Harder Than Ever Before.

Heck, they have a division within their offices dedicated to doing just that. Naughty Dog's Christophe Balestra wants to absolutely clarify that Uncharted 2: Among Thieves is impossible on the XBOX 360.
[quote]
"First of all, we fill the Blu-ray 100 percent," Balestra said. "We have no room left on this one."</blockquote>

Balestra also goes on to clarify that if the original Uncharted used around 30% of the Playstation 3's SPUs, Uncharted 2 will take up all 100%.

Magic.